Their children:
Hitomi
Keitaro
Seijuro Hiko - Kenshin's old master
Hikaru Hiko - His wife (m. 1878)
Mikiko Yoshida Himura - Hiko's great-niece and Keitaro's wife.
Saitoh Hajime (Goro Fujita) - Once a leader of the Shinsengumi, now a trusted inspector in the police force.
Tokio Fujita - His first wife.
Their children:
Kaede
Nobuharo
Mineko
Masami
Ryushi
Sachi
Daisuke - Hitomi's husband.
Souzou Sagara - The Captain of the Sekihotai
Moriko Sagara - Captain Sagara's sister and Saitoh's second wife (m. ?)
Kiyoshi Sagara - Moriko and Saitoh's son.
Hanako Omari Sagara - Kiyoshi's wife.
Moneko - Kiyoshi and Hanako's daughter.
Sanosuke Sagara - He also needs no introduction!
Tomiko Sagara - His wife (m. 1882)
Aoshi Shinomori - The leader of the Oniwaban Group
Misao Makimachi Shinomori - Aoshi's wife
Isamu Shinomori - Their daughter
Kaoru Kamiya - Master of the Kamiya Kasshin style in Tokyo
Yahiko Myojin - Kaoru's first apprentice
Tsubame Sanzo Myojin - His wife
Megumi Takani - The medicine chest! (Sanosuke-ism)